TY - JOUR KW - General Biochemistry, Genetics and Molecular Biology KW - General Medicine AU - Kwizera R AU - Mande E AU - Omali D AU - Okurut S AU - Nabweyambo S AU - Nabatanzi R AU - Nakanjako D AU - Meya DB AB - Abstract Background Translational research is a process of applying knowledge from basic biology and clinical trials to techniques and tools that address critical medical needs. Translational research is less explored in the Ugandan health system, yet, it is fundamental in enhancing human health and well-being. With the current high disease burden in Uganda, there are many opportunities for exploring, developing and utilising translational research. Main body In this article, we described the current state, barriers and opportunities for translational research in Uganda. We noted that translational research is underutilised and hindered by limited funding, collaborations, laboratory infrastructure, trained personnel, equipment and research diversity. However, with active collaborations and funding, it is possible to set up and develop thriving translational research in Uganda. Researchers need to leverage existing international collaborations to enhance translational research capacity development. Conclusion Expanding the integration of clinical and translational research in Uganda health care system will improve clinical care. BT - Journal of Translational Medicine DO - 10.1186/s12967-021-02747-z IS - 1 LA - eng N2 - Abstract Background Translational research is a process of applying knowledge from basic biology and clinical trials to techniques and tools that address critical medical needs. Translational research is less explored in the Ugandan health system, yet, it is fundamental in enhancing human health and well-being. With the current high disease burden in Uganda, there are many opportunities for exploring, developing and utilising translational research. Main body In this article, we described the current state, barriers and opportunities for translational research in Uganda. We noted that translational research is underutilised and hindered by limited funding, collaborations, laboratory infrastructure, trained personnel, equipment and research diversity. However, with active collaborations and funding, it is possible to set up and develop thriving translational research in Uganda. Researchers need to leverage existing international collaborations to enhance translational research capacity development. Conclusion Expanding the integration of clinical and translational research in Uganda health care system will improve clinical care. PB - Springer Science and Business Media LLC PY - 2021 T2 - Journal of Translational Medicine TI - Translational research in Uganda: linking basic science to bedside medicine in a resource limited setting UR - https://link.springer.com/content/pdf/10.1186/s12967-021-02747-z.pdf VL - 19 SN - 1479-5876 ER -