TY - JOUR
KW - Public Health, Environmental and Occupational Health
KW - Parasitology
KW - Infectious Diseases
KW - General Medicine
AU - Oladele RO
AU - Ly F
AU - Sow D
AU - Akinkugbe AO
AU - Ocansey BK
AU - Fahal A
AU - van de Sande WWJ
AB - Abstract
Background
Mycetoma is a neglected disease, which is socioeconomically important, and with the possibility of permanent disability in infected persons if not treated early. This is especially true in resource-limited settings such as West Africa, where there is a lack of facilities and skilled personnel to make a definitive laboratory diagnosis. Countries in West Africa have similar climatic conditions to Sudan. The majority of patients seek medical care very late, when there is already bone involvement, resulting in amputations. This results in poor capture of the true burden of the problem in the literature.
Methods
A review of the literature revealed about 2685 documented cases in West Africa from 1929 to 2020; from 15 out of 16 countries, Senegal accounted for 74.1% (1943) of cases in the subregion.
Results
The majority of lesions were found on the foot; however, other body parts were also reported. Rural dwellers accounted for most cases. Only 547 (20.4%) cases had identified isolates reported. Actinomycetoma accounted for 47.9% of cases, eumycetoma 39.7% and unidentified pathogens 12.4%. Actinomadura pelletieri was the predominant pathogen isolated (21.4%; 117 isolates).
Conclusion
There is a dire need for capacity building, provision of facility and health education to raise awareness of this debilitating disease in West Africa.
BT - Transactions of The Royal Society of Tropical Medicine and Hygiene
DO - 10.1093/trstmh/trab032
IS - 4
LA - eng
N2 - Abstract
Background
Mycetoma is a neglected disease, which is socioeconomically important, and with the possibility of permanent disability in infected persons if not treated early. This is especially true in resource-limited settings such as West Africa, where there is a lack of facilities and skilled personnel to make a definitive laboratory diagnosis. Countries in West Africa have similar climatic conditions to Sudan. The majority of patients seek medical care very late, when there is already bone involvement, resulting in amputations. This results in poor capture of the true burden of the problem in the literature.
Methods
A review of the literature revealed about 2685 documented cases in West Africa from 1929 to 2020; from 15 out of 16 countries, Senegal accounted for 74.1% (1943) of cases in the subregion.
Results
The majority of lesions were found on the foot; however, other body parts were also reported. Rural dwellers accounted for most cases. Only 547 (20.4%) cases had identified isolates reported. Actinomycetoma accounted for 47.9% of cases, eumycetoma 39.7% and unidentified pathogens 12.4%. Actinomadura pelletieri was the predominant pathogen isolated (21.4%; 117 isolates).
Conclusion
There is a dire need for capacity building, provision of facility and health education to raise awareness of this debilitating disease in West Africa.
PB - Oxford University Press (OUP)
PY - 2021
SP - 328
EP - 336
T2 - Transactions of The Royal Society of Tropical Medicine and Hygiene
TI - Mycetoma in West Africa
VL - 115
SN - 0035-9203, 1878-3503
ER -