TY - JOUR KW - Organic Chemistry KW - Computer Science Applications KW - Drug Discovery KW - General Medicine AU - Aborode AT AU - Fajemisin EA AU - Aiyenuro EA AU - Alakitan M AU - Ariwoola MO AU - Imisioluwa JO AU - Rafiu R AU - Alexiou A AB -

Abstract: Neglected Tropical Diseases (NTDs) are a group of twenty (20) chronic, communicable, infectious diseases endemic to the tropics and sub-tropics climate countries which are intimately associated with poverty, poor sanitation, limited clean water, and healthcare delivery; and dwellers live in proximity to pathogens and diseases vectors. The pathogens are protozoans, bacteria, helminths, fungi, and viruses. NTDs currently affects about one billion people globally, out of which 500 million are Africans living in rural settlements with low political voice and support. In recent years, NTDs have received little research recognition, development, and funding because more research efforts by global health stakeholders are focused on recognized diseases like Cancers, Hepatitis, Tuberculosis, Acquired Immune-Deficiency Syndrome (AIDS), and Malaria that affects most developed countries. The emergence of the viral novel COVID-19 will exacerbate the burden of NTDs on disadvantaged communities as global health efforts are again focused on COVID-19 clearance in terms of research and development to find a drug/vaccine amidst other investigations on recognized infections. This development can result in high death tolls due to NTDs if control measures aren't prioritized now. This perspective piece addresses the need for NTDs control amidst COVID-19 clearance efforts to mitigate another viral health crisis in Africa.

BT - Combinatorial Chemistry & High Throughput Screening DO - 10.2174/1386207325666220427123349 LA - eng N2 -

Abstract: Neglected Tropical Diseases (NTDs) are a group of twenty (20) chronic, communicable, infectious diseases endemic to the tropics and sub-tropics climate countries which are intimately associated with poverty, poor sanitation, limited clean water, and healthcare delivery; and dwellers live in proximity to pathogens and diseases vectors. The pathogens are protozoans, bacteria, helminths, fungi, and viruses. NTDs currently affects about one billion people globally, out of which 500 million are Africans living in rural settlements with low political voice and support. In recent years, NTDs have received little research recognition, development, and funding because more research efforts by global health stakeholders are focused on recognized diseases like Cancers, Hepatitis, Tuberculosis, Acquired Immune-Deficiency Syndrome (AIDS), and Malaria that affects most developed countries. The emergence of the viral novel COVID-19 will exacerbate the burden of NTDs on disadvantaged communities as global health efforts are again focused on COVID-19 clearance in terms of research and development to find a drug/vaccine amidst other investigations on recognized infections. This development can result in high death tolls due to NTDs if control measures aren't prioritized now. This perspective piece addresses the need for NTDs control amidst COVID-19 clearance efforts to mitigate another viral health crisis in Africa.

PB - Bentham Science Publishers Ltd. PY - 2022 T2 - Combinatorial Chemistry & High Throughput Screening TI - Neglected Tropical Diseases (NTDs) and COVID-19 Pandemic in Africa: Special Focus on Control Strategies VL - 25 SN - 1386-2073 ER -