TY - JOUR KW - Cardiology and Cardiovascular Medicine KW - General Medicine KW - the NET-Heart Project AU - Miranda-Arboleda AF AU - Gonzalez-Barrera LG AU - Liblik K AU - Farina J AU - Zaidel EJ AU - Saldarriaga C AU - Zhou Z AU - Al-Rawi R AU - López-López JP AU - Juarez-Lloclla JP AU - Gupta S AU - Prabhakaran D AU - Kumar RK AU - Sosa-Liprandi Á AU - Baranchuk A AB -

Sudden cardiac death (SCD) is responsible for approximately 6% of global mortality and 25% of cardiovascular (CV) deaths. SCD has been traditionally linked to coronary artery disease, valvular heart disease, cardiomyopathies, and genetic arrhythmia disorders. However, advancements in care for these diseases have not translated to a proportional reduction in SCD. This suggests an important role of underrecognized contributing pathologies. Neglected tropical diseases (NTDs) are a group of illnesses prevalent in tropical and sub-tropical regions which have been understudied partially due to their high prevalence in marginalized populations. The relationship between SCD and Chagas disease has been well-established, though emerging literature suggests that other NTDs with CV involvement may lead to fatal arrhythmias. Additionally, specific therapies for a subset of NTDs put patients at increased risk of malignant arrhythmias and other cardiac complications. This review aims to summarize the association between a group of selected NTDs and SCD.

BT - Reviews in Cardiovascular Medicine DO - 10.31083/j.rcm2307254 IS - 7 LA - eng N2 -

Sudden cardiac death (SCD) is responsible for approximately 6% of global mortality and 25% of cardiovascular (CV) deaths. SCD has been traditionally linked to coronary artery disease, valvular heart disease, cardiomyopathies, and genetic arrhythmia disorders. However, advancements in care for these diseases have not translated to a proportional reduction in SCD. This suggests an important role of underrecognized contributing pathologies. Neglected tropical diseases (NTDs) are a group of illnesses prevalent in tropical and sub-tropical regions which have been understudied partially due to their high prevalence in marginalized populations. The relationship between SCD and Chagas disease has been well-established, though emerging literature suggests that other NTDs with CV involvement may lead to fatal arrhythmias. Additionally, specific therapies for a subset of NTDs put patients at increased risk of malignant arrhythmias and other cardiac complications. This review aims to summarize the association between a group of selected NTDs and SCD.

PB - IMR Press PY - 2022 EP - 254 T2 - Reviews in Cardiovascular Medicine TI - Neglected Tropical Diseases and Sudden Cardiac Death: The NET-Heart Project UR - https://www.imrpress.com/journal/RCM/23/7/10.31083/j.rcm2307254/pdf VL - 23 SN - 1530-6550 ER -