In this paper, we study optimal control and cost-effectiveness of several schistosomiasis control strategies. The control strategies investigated are health education, molluscicide use, and the combination of health education and molluscicide intervention. To solve the optimal control problem, we use Pontryagin’s maximum principle. We compute the average cost- effectiveness ratio (ACER) and incremental cost-effectiveness ratio (ICER) to identify the most cost-effective strategy. The results show that the most cost-effective strategy to control schistosomiasis in the region with adequate sanitation is health education intervention. On the other hand, molluscicide intervention is the most cost-effective strategy to control schistosomiasis in the region with inadequate sanitation. Furthermore, the most effective strategy to eliminate schistosomiasis is the combination of health education and molluscicide intervention.
BT - THE 4TH INTERNATIONAL CONFERENCE ON NUCLEAR ENERGY TECHNOLOGIES AND SCIENCES (ICoNETS) 2021 DO - 10.1063/5.0082984 LA - eng N2 -In this paper, we study optimal control and cost-effectiveness of several schistosomiasis control strategies. The control strategies investigated are health education, molluscicide use, and the combination of health education and molluscicide intervention. To solve the optimal control problem, we use Pontryagin’s maximum principle. We compute the average cost- effectiveness ratio (ACER) and incremental cost-effectiveness ratio (ICER) to identify the most cost-effective strategy. The results show that the most cost-effective strategy to control schistosomiasis in the region with adequate sanitation is health education intervention. On the other hand, molluscicide intervention is the most cost-effective strategy to control schistosomiasis in the region with inadequate sanitation. Furthermore, the most effective strategy to eliminate schistosomiasis is the combination of health education and molluscicide intervention.
PB - AIP Publishing PY - 2022 T2 - THE 4TH INTERNATIONAL CONFERENCE ON NUCLEAR ENERGY TECHNOLOGIES AND SCIENCES (ICoNETS) 2021 TI - Optimal control problem and cost-effectiveness analysis of schistosomiasis model UR - https://aip.scitation.org/doi/pdf/10.1063/5.0082984 SN - 0094-243X ER -