01559nas a2200277   4500000000100000008004100001260001300042653001000055653001600065653002500081653001100106653001200117653001200129653002300141653002600164653002000190653002900210653001300239653002400252100002000276245011100296300001000407490000600417520084400423022001401267       1984                            d  c1984 Mar10aChild10aHepatitis B10aHepatitis B Antigens10aHumans10aleprosy10aMalaria10aNephrotic Syndrome10aSalmonella Infections10aschistosomiasis10aStreptococcal Infections10aSyphilis10aYersinia Infections1 aAbdurrahman M B00aThe role of infectious agents in the aetiology and pathogenesis of childhood nephrotic syndrome in Africa.  a100-90 v83 a<p>Childhood nephrotic syndrome is common in Africa where infectious agents are prevalent. This paper reviews the possible aetiological role of infectious agents in childhood nephrotic syndrome in Africa. There is a strong association, possibly causal, between childhood nephrotic syndrome on the one hand and Plasmodium malariae, Schistosoma mansoni and hepatitis B antigens on the other. Beta-haemolytic streptococci are less strongly associated with nephrotic syndrome, and a few other organisms are suspect. The many ubiquitous infectious agents and the prevalence of multiple infections make it difficult to define the role of any single infectious agent or to determine the interaction between the various agents. Control or eradication of infectious diseases should lower the incidence of childhood nephrotic syndrome in Africa.</p>  a0163-4453