01088nas a2200133   4500000000100000008004100001653004000042653002200082100001700104245006500121856006700186520068700253022001400940       2019                            d10aHuman African Trypanosomiasis (HAT)10aSleeping sickness1 aKennedy PG E00aUpdate on human African trypanosomiasis (sleeping sickness).  uhttps://link.springer.com/article/10.1007%2Fs00415-019-09425-73 a<p>Human African trypanosomiasis (HAT), also known as sleeping sickness, is one of the Africa's 'neglected diseases' and is caused by infection with protozoan parasites of the Trypanosoma genus. Transmitted by the bite of the tsetse fly, it puts 70 million people at risk throughout sub-Saharan Africa and is usually fatal if untreated or inadequately treated. In this brief overview, some important recent developments in this disease are outlined. These cover various aspects including a reduction in disease incidence, newly recognised parasite reservoir sites in humans, disease outcome, novel diagnostic methods, new and improved treatment, and disease neuropathogenesis.</p>
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