TY - JOUR KW - Neglected tropical diseases (NTDs) KW - Zika virus KW - Environmental factors KW - Social Change KW - Women KW - Brazil AU - Ali S AU - Gugliemini O AU - Harber S AU - Harrison A AU - Houle L AU - Ivory J AU - Kersten S AU - Khan R AU - Kim J AU - LeBoa C AU - Nez-Whitfield E AU - O'Marr J AU - Rothenberg E AU - Segnitz M AU - Sila S AU - Verwillow A AU - Vogt M AU - Yang A AU - Mordecai EA AB -

Since Zika virus (ZIKV) was detected in Brazil in 2015, it has spread explosively across the Americas and has been linked to increased incidence of microcephaly and Guillain-Barré syndrome (GBS). In one year, it has infected over 500,000 people (suspected and confirmed cases) in 40 countries and territories in the Americas. Along with recent epidemics of dengue (DENV) and chikungunya virus (CHIKV), which are also transmitted by Aedes aegypti and Ae. albopictus mosquitoes, the emergence of ZIKV suggests an ongoing intensification of environmental and social factors that have given rise to a new regime of arbovirus transmission. Here, we review hypotheses and preliminary evidence for the environmental and social changes that have fueled the ZIKV epidemic. Potential drivers include climate variation, land use change, poverty, and human movement. Beyond the direct impact of microcephaly and GBS, the ZIKV epidemic will likely have social ramifications for women's health and economic consequences for tourism and beyond.

BT - PLoS neglected tropical diseases C1 -

http://www.ncbi.nlm.nih.gov/pubmed/28182667?dopt=Abstract

DO - 10.1371/journal.pntd.0005135 IS - 2 J2 - PLoS Negl Trop Dis LA - eng N2 -

Since Zika virus (ZIKV) was detected in Brazil in 2015, it has spread explosively across the Americas and has been linked to increased incidence of microcephaly and Guillain-Barré syndrome (GBS). In one year, it has infected over 500,000 people (suspected and confirmed cases) in 40 countries and territories in the Americas. Along with recent epidemics of dengue (DENV) and chikungunya virus (CHIKV), which are also transmitted by Aedes aegypti and Ae. albopictus mosquitoes, the emergence of ZIKV suggests an ongoing intensification of environmental and social factors that have given rise to a new regime of arbovirus transmission. Here, we review hypotheses and preliminary evidence for the environmental and social changes that have fueled the ZIKV epidemic. Potential drivers include climate variation, land use change, poverty, and human movement. Beyond the direct impact of microcephaly and GBS, the ZIKV epidemic will likely have social ramifications for women's health and economic consequences for tourism and beyond.

PY - 2017 EP - e0005135 T2 - PLoS neglected tropical diseases TI - Environmental and social change drive the explosive emergence of Zika virus in the Americas. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300271/pdf/pntd.0005135.pdf VL - 11 SN - 1935-2735 ER -