The burden of human African trypanosomiasis.

Version imprimable
TitreThe burden of human African trypanosomiasis.
Type de PublicationJournal Article
AuteursFèvre EM, Wissmann BV, Welburn SC, Lutumba P
Abbrev. JournalPLoS Negl Trop Dis
Périodique / RevuePLoS neglected tropical diseases
Année de Publication2008
Volume2
Ticket12
Paginatione333
Langue de Publicationeng
Mots-clésAcquired Immunodeficiency Syndrome, Africa South of the Sahara, Animals, Cost of Illness, Disabled Persons, Humans, Malaria, Parasitic Diseases, Rural Population, Tropical Climate, Tropical Medicine, Trypanosoma brucei gambiense, Trypanosoma brucei rhodesiense, Trypanosomiasis, African, Zoonoses
Résumé

Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in sub-Saharan Africa, with an emphasis on the disability-adjusted life year (DALY), data sources, and methodological issues relating to the use of this metric for assessing the burden of this disease. We highlight areas where data are lacking to properly quantify the impact of these diseases, mainly relating to quantifying under-reporting and disability associated with infection, and challenge the HAT research community to tackle the neglect in data gathering to enable better evidence-based assessments of burden using DALYs or other appropriate measures.

PubMed URL

http://www.ncbi.nlm.nih.gov/pubmed/19104653?dopt=Abstract

DOI10.1371/journal.pntd.0000333
Link to full texthttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602597/pdf/pntd.0000333.pdf
PubMed Central IDPMC2602597
Grant List / / Wellcome Trust / United Kingdom