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Publication

Herbs as old potential treatments for lymphedema management: A systematic review

Abstract
Introduction
Herbs have been reported to be effective in reducing lymphedema burden. This paper aimed to review literature reporting on herbs for lymphedema treatment.

Methods
A systematic review was performed using the PRISMA guideline. Clinical studies on herbal intervention and lymphedema were included. Evidence on the effectiveness of herbal interventions for desired outcomes including reduction of edema volume, other symptoms, quality of life and inflammation were collected and assessed in detail.

Results
In all twenty studies were included in this review. Of these 14 studies were randomized clinical trials and the rest were prospective pilot studies. Herbal treatment was reported for breast cancer-related lymphedema in most studies and coumarin was the most reported herb that used for lymphedema management. Edema volume reduction (17 out of 20) and symptoms improvement (15 out of 20) were the outcomes reported in most studies.

Conclusion
Phytochemicals can be a promising pharmacotherapy for lymphedema management. However, further evidence is needed to establish definite effectiveness for the use of herbal remedies for lymphedema management.

More information

Type
Journal Article
Author
Sheikhi-Mobarakeh Z
Yarmohammadi H
Mokhatri-Hesari P
Fahimi S
Montazeri A
Heydarirad G
Year of Publication
2020
Journal
Complementary Therapies in Medicine
Number of Pages
102615
Language
eng
ISSN Number
0965-2299
DOI
10.1016/j.ctim.2020.102615
Publication Language
eng