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Onchocerciasis dynamics: modelling the effects of treatment, education and vector control.

Abstract

A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin.

More information

Type
Journal Article
Author
Hassan A
Shaban N

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