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Schistosomiasis Consortium for Operational Research and Evaluation: Mission Accomplished.

Abstract

The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE), a program focusing on schistosomiasis control in sub-Saharan Africa between 2008 and 2019, investigated ways to improve coverage and efficacy of ongoing chemotherapy programs and concluded that because of continued transmission, mass distribution of praziquantel cannot eliminate the disease without complementary control activities. Schistosomiasis Consortium for Operational Research and Evaluation's activities comprised large-scale, multicountry field studies comparing various mass drug administration strategies and some specific research avenues, such as assessment of high-sensitivity diagnostics, identification of hotspots, quantification of the role of the snail host, predictive modeling, and changes in schistosome population genetics under drug pressure. The discoveries made and the insights gained regarding cost-effective strategies for delivering preventive chemotherapy should assist policy makers to develop guidelines for the control and ultimate elimination of schistosomiasis.

More information

Type
Journal Article
Author
Bergquist RN
Year of Publication
2020
Journal
The American journal of tropical medicine and hygiene
Date Published
05/2020
Language
eng
ISSN Number
1476-1645
DOI
10.4269/ajtmh.19-0838
Alternate Journal
Am. J. Trop. Med. Hyg.
PMID
32400351
Publication Language
eng