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The global burden of disease study 2010: Interpretation and implications for the neglected tropical diseases.

Abstract

The publication of the Global Burden of Disease Study 2010 (GBD 2010) and the accompanying collection of Lancet articles in December 2012 provided the most comprehensive attempt to quantify the burden of almost 300 diseases, injuries, and risk factors, including neglected tropical diseases (NTDs) [1]–[3]. The disability-adjusted life year (DALY), the metric used in the GBD 2010, is a tool which may be used to assess and compare the relative impact of a number of diseases locally and globally [4]–[6]. Table 1 lists the major NTDs as defined by the World Health Organization (WHO) [7] and their estimated DALYs [1]. With a few exceptions, most of the NTDs currently listed by the WHO [7] or those on the expanded list from PLOS Neglected Tropical Diseases [8] are disablers rather than killers, so the DALY estimates represent one of the few metrics available that could fully embrace the chronic effects of these infections.

More information

Type
Journal Article
Author
Hotez PJ
Alvarado M
áñez G
Bolliger I
Bourne R
Boussinesq M
Brooker SJ
Brown AS
Buckle G
Budke CM
Carabin H
Coffeng LE
èvre EM
ürst T
Halasa YA
Jasrasaria R
Johns NE
Keiser J
King CH
Lozano R
Murdoch ME
O'Hanlon S
Pion SD S
Pullan RL
Ramaiah KD
Roberts T
Shepard DS
Smith JL
Stolk WA
Undurraga EA
Utzinger J
Wang M
Murray CJ L
Naghavi M
Year of Publication
2014
Journal
PLoS neglected tropical diseases
Volume
8
Issue
7
Number of Pages
e2865
Language
eng
DOI
10.1371/journal.pntd.000286510.1371
Alternate Journal
PLoS Negl Trop Dis
Publication Language
eng