|Title||Loa loa microfilariae in skin snips: consequences for onchocerciasis monitoring and evaluation in L. loa endemic areas.|
|Publication Type||Journal Article|
|Authors||Nana-Djeunga HC, Fossuo-Thotchum F, Pion SD, Chesnais CB, Kubofcik J, Mackenzie CD, Klion AD, Boussinesq M, Nutman TB, Kamgno J|
|Abbrev. Journal||Clin. Infect. Dis.|
|Journal||Clinical infectious diseases : an official publication of the Infectious Diseases Society of America|
|Year of Publication||2019|
|Keywords||Loa loa, Microfilariae, Monitoring and evaluation, Onchocerciasis|
The specificity of skin snips for onchocerciasis diagnosis is considered to be almost 100%. In this study, molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for onchocerciasis diagnostic testing in Loa-endemic areas.