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Loa loa microfilariae in skin snips: consequences for onchocerciasis monitoring and evaluation in L. loa endemic areas.

Abstract

The specificity of skin snips for onchocerciasis diagnosis is considered to be almost 100%. In this study, molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for onchocerciasis diagnostic testing in Loa-endemic areas.

More information

Type
Journal Article
Author
Nana-Djeunga HC
Fossuo-Thotchum F
Pion SD
Chesnais CB
Kubofcik J
Mackenzie CD
Klion AD
Boussinesq M
Nutman TB
Kamgno J
Year of Publication
2019
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Language
eng
ISSN Number
1537-6591
DOI
10.1093/cid/ciz172
Alternate Journal
Clin. Infect. Dis.
Publication Language
eng

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