A new definition of human health is needed to better implement One Health

Since the COVID-19 pandemic, One Health approaches¹ have revived attention to the interdependence of human, animal, and ecosystem health. However, human health is still predominantly viewed through the prism of disease affecting humans and related care activities, as illustrated by health expenditure and health regulation. This approach is now overly restrictive since interdependencies and holistic approaches are crucial for the prevention and preservation of human health, particularly in relation to interlinked climate, biodiversity, pollution, and health crises. We claim that redefining WHO's definition of human health will facilitate actual implementation of One Health approaches in the medical field, improve pandemic prevention, and reflect the many ways in which health determinants have evolved. Although the funding and very existence of WHO are under attack, with dramatic consequences on worldwide global health, WHO should seize the opportunity to change the definition of human health and thereby reinvent itself, showing its ability to evolve with the international context, base its recommendations and policies on updated science, and promote multilateralism and its values.